Effective Strategies for the Management of Pyoderma Gangrenosum

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Effective Strategies for the Management of Pyoderma Gangrenosum.

BACKGROUND Pyoderma gangrenosum (PG) is an inflammatory disease characterized by painful ulcerations. It is often associated with other systemic inflammatory diseases, especially inflammatory bowel disease (IBD) and autoimmune arthritis. THE PROBLEM PG does not have characteristic serologic or histologic features. Therefore, other potential causes such as malignancy, vasculitis, infection, an...

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Diagnosis and management of parastomal pyoderma gangrenosum

Parastomal pyoderma gangrenosum (PPG) is an unusual neutrophilic dermatosis characterized by painful, necrotic ulcerations occurring in the area surrounding an abdominal stoma. It typically affects young to middle-aged adults, with a slight female predominance. The underlying etiology for PPG remains enigmatic but aberrant immune response to injury may play a pivotal role. The reported risk fac...

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Pyoderma gangrenosum.

Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, noninfective chronic inflammatory skin disorder of unknown etiology. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, haematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violace...

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Mycophenolate mofetil is an effective treatment for peristomal pyoderma gangrenosum.

An 18-year-old woman with Crohn disease was referred by her gastrointestinal surgeon for treatment of possible peristomal pyoderma gangrenosum (PPG). She had undergone a total proctocolectomy with ileoanal anastomosis when she was 10 years old. Her inflammatory bowel disease (IBD) had been quiescent for a few years; however, she had an acute onset of anal fistulas and pouchitis, which led to a ...

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Nicotine for pyoderma gangrenosum.

A 35-year-old man with no past medical illness developed bloody diarrhea with up to 12 loose stools per day and abdominal pain in February 1984. He had smoked 1 pack of cigarettes per day for 16 years until he stopped smoking 2 months prior to the onset of his illness. In March 1984, he was hospitalized because of toxic dilatation of the colon (toxic megacolon). Treatment consisted of intraveno...

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ژورنال

عنوان ژورنال: Advances in Wound Care

سال: 2012

ISSN: 2162-1918,2162-1934

DOI: 10.1089/wound.2011.0339